Mimicking Tumor Metabolism Allows NK Cells to Thrive in the Hostile Tumor Microenvironment

Researchers Sophie Poznanski and Dr. Ali Ashkar demonstrate that immune cell metabolism is a central factor in determining NK cell inhibition or cytotoxic function in the tumor microenvironment (TME).

 Posted: October 26, 2021

Sophie Poznanski (left) and Dr. Ali Ashkar (right)

Dr. Seung-Hwan Lee (left) and Dr. Abrar Khan (right)

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Uncovering mechanisms of NK cell metabolic reprogramming during viral infection

 Posted: September 24, 2021

Researchers Dr. Abrar Khan, Saeedah Almutairi and Dr. Seung-Hwan Lee explore the mechanisms of NK cell metabolic reprogramming during MCMV infection in their recent Frontiers in Immunology publication.

Revealing the link between NKG2C genotype and susceptibility to HIV infection 

Researchers Khlood Alsulami and Dr. Nicole Bernard analyze the link between NKG2C genotype and susceptibility and protection to HIV infection in recent Journal of Virology publication. 

 Posted: July 05, 2021

Khlood Alsulami (left) and Dr. Nicole Bernard (right)

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Deciphering how cell membrane lipid scrambling regulates NK cell activation

Researchers Dr. Ning Wu, Hua Song, and Dr. André Veillette elucidate the mechanism by which NK cell lipid scrambling regulates NK cell activation and cytotoxicity in recent Cellular & Molecular Immunology publication. 

 Posted: April 27, 2021

Dr. Ning Wu (left) and Dr. André Veillette (right)