We would like to start off the year with discussion exploring the inherent ability of NK cells to resist being infected by virus. There are a number of viruses that infect immune cells: eg. HIV infection of CD4 T cells and DCs, influenza or ZIKV infection of macrophages, and EBV infection of B ce

At the Universite de Sherbrooke, we have observed accumulation of fatty acids in NK cells and this altered metabolism impairs their ability to clear tumors in the postoperative period.

This month we would like to open discussion on NK cell metabolism. There is a growing understanding of the critical role cell metabolism plays in regulating immune cell function. For instance, in T cells and macrophages, it is now understood that modulating cell metabolism is sufficient to determ